[Calcinosis cutis in a patient with systemic lupus erythematosus].

We present the case of a 36 year old woman with systemic lupus erythematosus with hematological, skin and joint affection, with an onset 21 years prior. The immunologic study showed positive ANA (titer 1:1,000, homogeneous pattern), anti-DNA, anti-ENA and anti-Ro (SSA). She presented multiple hard subcutaneous nodules on the trunk and extremities since 10 years prior, which tended to conglomerate at the buttocks, hips and thighs forming extensive plaques. Throughout the last year she has presented a progressively larger ulcer with a serous exudate over the lesions of the right thigh. Cultures were positive for Staphylococcus aureus. A simple abdomen x-ray (Figure 1) and a tomography (Figure 2) revealed multiple and extensive subcutaneous calcifications (arrows). In spite of treatment with diltiazem, calcifications persist and the ulcer progressed rapidly. Diagnosis: calcinosis cutis